ASCA IgA Kit
This assay is intended as an aid in the diagnosis of inflammatory bowel disease (IBD), specifically Crohn's disease. The kit is designed for the detection and quantitation of IgA anti-Saccharomyces cerevisiae antibodies in human serum.
Antigen
The microwells are precoated with mannan isolated from Saccharomyces cerevisiae.
Calibration
The assay is calibrated to U/mL against an arbitrary internal reference calibrator, as no internationally recognised reference preparation is currently available. A 5 point calibration curve is generated. A cut-off control is provided if being used as a screening assay.
Result Interpretation
Quantitative Assay
| Result | Interpretation |
|---|---|
| < 7.0 U/mL | Negative |
| > 7.0 U/mL | Positive |
Screening Assay
| Result | Interpretation | Action |
|---|---|---|
|
OD greater than cut-off control
|
Suspected of having ASCA
|
Test in the quantitative assay if value required |
| OD less than or equal to cut-off control | Negative | Report as negative |
Measuring Range
1.23 - 100 U/mL
Sensitivity
0.93 U/mL
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