Automated Analyzer for Serum/Plasma Protein Analysis

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The SPAPLUS is a dedicated analyzer supplied by Binding Site in the USA and Canada (Click here for SPAPLUS in Germany and Austria). Binding Site offers the SPAPLUS analyzer together with Freelite serum free light chain assays to improve the diagnosis and monitoring of Multiple Myeloma and AL amyloidosis (Freelite assays are available to run on a range of other analyzers too).
NEW IgG Subclass and Cystatin C assays for the SPAPLUS are also available now.
The SPAPLUS offers the following advantages:
Confidence
- Easy to use
- Autodilution (1/10)
- Auto rerun of out of range samples (Neat or 1/100)

- Antigen excess detection
- Auto calculation of the Freelite κ/λ ratio
- Internal QC program with Levy-Jennings graphing
- Reagents cooled to 10 + 2ºC
Speed & Productivity
- 80 Freelite tests per hour
- 10.5 minute incubation - 15 minutes to first result - every 30 seconds thereafter
- Continuous sample loading
- Patient ID and reagent bar code reader
- Bidirectional RS232 LIS Interface
- Auto washing, liquid level sensing probes
Built-In Reliability
- Low maintenance

- Unique dual chamber cuvette
- Dual chamber pressure mixing to minimize carry over
- High temperature cuvette wash to extend cuvette life
- Long life plastic cuvettes minimize replacement costs
- Cuvette flagging when replacement is required
- Modular design for easy maintenance
Technical Support and Service
Our highly qualified Technical Specialists and Field Service Engineers provide excellent support in the field.
The Binding Site Service Team provides:
- Validation support
- On-site service
- Advanced user training
Experienced In-House Technical Support
The Technical Support Hotline is staffed by a team of trained specialists able to troubleshoot and resolve most calls over the telephone. Overnight shipment of replacement modular components ensures a rapid response time and delivers maximum operating efficiency for your Binding Site SPAPLUS™.
SPAPLUS Analyzer Specification
| Serum Assay Parameters | Kappa | Lambda |
|---|---|---|
| Measuring Range @ 1/10 | 4-180 mg/L | 6-220 mg/L |
| Measuring Range @ 1/100 | 40-1800 mg/L | 60-2200 mg/L |
| Sensitivity (undiluted) | 0.4 mg/L | 0.6 mg/L |
| Sample Volume | 15µL | 6.5µL |
| Serum Assay Parameters | Cystatin C |
|---|---|
| Measuring Range @ 1/10 | 0.4-7.35 mg/L |
| Sensitivity (undiluted) | 0.04 mg/L |
| Serum Assay Parameters | IgG | IgG1 | IgG2 | IgG3 | IgG4 |
|---|---|---|---|---|---|
| Measuring Range @ 1/10 (g/L) | 1.65 - 35.0 | 1.5 - 36.0 | 0.2 - 7.0 | 0.055 - 1.0 | 0.03 - 0.85 |
| Sensitivity (undiluted) g/L | 0.165 | 0.15 | 0.02 | 0.0055 | 0.003 |
| Analyser | Description | Pack | Code |
|---|---|---|---|
| Binding Site SPAPLUS™ |
Freelite Kappa Kit | 1 X 100 test | LK016.S |
| Freelite Lambda Kit | 1 X 100 test | LK018.S | |
| Cystatin C | 1 x 100 test | LK048.S | |
| IgG Kit | 1 X 100 test | NK004.S | |
| IgG1 Kit | 1 X 100 test | NK006.S | |
| IgG2 Kit | 1 X 100 test | NK007.S | |
| IgG3 latex Kit | 1 X 100 test | LK008.S | |
| IgG4 latex Kit | 1 X 100 test | LK009.S |
Please contact us for more information or to discuss a SPAPLUS contract
SPAPLUS™ and Freelite™ are trademarks of The Binding Site Ltd, Birmingham, UK. Windows is a registered trademark of The Microsoft Corporation.

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