Automated Analyzer for Serum/Plasma Protein Analysis

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The SPAPLUS is a dedicated serum and protein analyzer supplied by Binding Site.
Binding Site's SPAPLUS is a compact, easy to use turbidimetric analyser providing a level of functionality usually seen only in larger analysers. The combination of an air mixing system, dual compartment reaction cuvettes and a hot water wash make the SPAPLUS ideal for Binding Site latex assays.
- Automatic antigen excess check
- Automated rerun & autodilution capability
- Windows® based software & bidirectional interface
St. Vincent's Comprehensive Cancer Center in New York, USA, were the first to install the SPAPLUS in November 2007 and feel that the instrument is 'more accurate, reproducible and reliable than the method previously in use'. Click here to read further details of their implementation of SPAPLUS.
The SPAPLUS offers the following advantages:
Confidence
- Easy to use
- Autodilution (1/10)
- Auto rerun of out of range samples (Neat or 1/100)

- Antigen excess detection
- Auto calculation of the Freelite™ κ/λ ratio
- Internal QC program with Levy-Jennings graphing
- Reagents cooled to 10 + 2ºC
Speed & Productivity
- 80 Freelite tests per hour
- 10.5 minute incubation - 15 minutes to first result - every 30 seconds thereafter
- Continuous sample loading
- Patient ID and reagent bar code reader
- Bidirectional RS232 LIS Interface
- Auto washing, liquid level sensing probes
Built-In Reliability
- Low maintenance

- Unique dual chamber cuvette
- Dual chamber pressure mixing to minimize carry over
- High temperature cuvette wash to extend cuvette life
- Long life plastic cuvettes minimize replacement costs
- Cuvette flagging when replacement is required
- Modular design for easy maintenance
Technical Support and Service
Our highly qualified Technical Specialists and Field Service Engineers provide excellent support in the field.
The Binding Site Service Team provides:
- Validation support
- On-site service
- Advanced user training
Experienced In-House Technical Support
The Technical Support Hotline is staffed by a team of trained specialists able to troubleshoot and resolve most calls over the telephone. Overnight shipment of replacement modular components ensures a rapid response time and delivers maximum operating efficiency for your Binding Site SPAPLUS™.
SPAPLUS Analyzer Specification
SPAPLUS Assays
The automated rerun capability of the SPAPLUS increases the measuring range significantly for each assay.
| Description | Pack | Code |
|---|---|---|
| Freelite Kappa Latex SPAPLUS kit Range 4-180 mg/L (1/10) Range 40-1800 mg/L (1/100) Sensitivity 0.4 mg/L | 100 test | LK016.S |
| Freelite Lambda Latex SPAPLUS kit Range 6-220 mg/L (1/10) Range 60-2200 mg/L (1/100) Sensitivity 0.6 mg/L | 100 test | LK018.S |
| Cystatin C Latex SPAPLUS kit Range 0.4-7.35 mg/L (1/10) Sensitivity 0.04 mg/L | 100 test | LK048.S |
| Beta-2 Microglobulin Latex SPAPLUS kit Range 0.6-20 mg/L (1/20) Sensitivity Serum 0.3 mg/L (1/10) Sensitivity Urine 0.03 mg/L (1/1) | 100 test | LK043.S |
| IgG SPAPLUS kit Range 1650-35000 mg/L (1/10) Sensitivity 165 mg/L | 100 test | NK004.S |
| IgG1 SPAPLUS kit Range 1500-36000 mg/L (1/10) Sensitivity 150 mg/L | 100 test | NK006.S |
| IgG2 SPAPLUS kit Range 200-7000 mg/L (1/10) Sensitivity 20 mg/L | 100 test | NK007.S |
| IgG3 SPAPLUS kit Range 55-1000 mg/L (1/10) Sensitivity 5.5 mg/L | 100 test | LK008.S |
| IgG4 SPAPLUS kit Range 30-850 mg/L (1/10) Sensitivity 3 mg/L | 100 test | LK009.S |
| IgA SPAPLUS kit Range 200-7000 mg/L (1/10) Sensitivity 200 mg/L | 100 test | NK010.S |
| IgM SPAPLUS kit Range 200-7500 mg/L (1/10) Sensitivity 100 mg/L | 100 test | NK012.S |
| New IgD SPAPLUS kit Range 7 - 210 mg/L (1/10) | 100 test | LK013.S |
| Tetanus toxoid Latex SPAPLUS kit Range 1.56-50 IU/mL | 1000 test | LK710.S |
Please enquire regarding new assays in development.
In development for 2010:
- Hevylite™ IgA kappa & lambda
- Hevylite™ IgG kappa & lambda
- Hevylite™ IgM kappa & lambda
- Complement CH50
- Complement C3
- Complement C4
To be confirmed:
- Hevylite™ IgD kappa & lambda
Please contact us for more information or to discuss a SPAPLUS contract
SPAPLUS is currently also available in UK, France, Germany, Austria and Spain. In other countries please check with your local Binding Site supplier.
SPAPLUS™ , Freelite™ and Hevylite™ are trademarks of The Binding Site Group Ltd, Birmingham, UK. Windows is a registered trademark of The Microsoft Corporation.

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